New Technology Accesses Small But Mighty Microorganisms
More medicines may be developed faster in the near future, thanks to new technology that harnesses the tiny particles that make drug development possible.Microorganisms grown in laboratories have been the starting point for many medicines we have today. However, many more microorganisms exist in nature that can’t be grown in a lab because they are too small, too fragile, or evolve too rapidly.
Also, microbes grown in culture behave differently than those extracted from the natural world, and are more limited in their ability to perform the chemical reactions that lead to drug discovery and product development.But Biosortia Pharmaceuticals has developed a novel way to access the previously hidden chemistry of microorganisms and capture small molecules directly from nature. Biosortia uses its technology to collect microbiomes in quantity and at quality, a concept known as microbiol mining. The microbiomes are becoming part of Biosortia’s growing library of patent able natural molecule activity and derivatives that can be used by various industries, including pharmaceutical, cosmetic, and agricultural, to solve problems and create products."Microbes are and have always been chemical researchers and factories of life," says Ross Youngs, founder and CEO of Biosortia.The ability of Biosortia to recover active microbiomes is creating "massive opportunities to explore the unknown," he says in a recent LinkedIn post. Biosortia’s microbiol mining approach has several advantages:
– More options;
Biosortia’s technology allows the company unprecedented access to previously unavailable molecules that have the potential for use in a range of industries, and can provide a genomic road map to accompany data on the activity of the chemistry.
– More efficiency;
Biosortia accesses material from the microbiol in days, compared to the years needed by other researchers. In addition, the cost of Biosortia technology is significantly lower than traditional methods of microorganism development.
– More success;
Small molecules accessed directly from the microbiol are more likely to be successful in clinical development than those cultured in a lab because they have reached their potential in nature. Biorsortia continues to expand and has secured four patents to date, as well as a pending contract with the Department of Homeland Security. The Company’s science team publication technology has been peer-reviewed and received an Editor’s Choice Award from the American Chemical Society.
The iPhone 11 Pro and the iPhone 11 Pro Max are smartphones designed, developed and marketed by Apple Inc. They are the 13th-generation flagships of the iPhone, succeeding the iPhone XS and iPhone XS Max. They were unveiled on September 10, 2019 alongside the lower-end model, the iPhone 11 at the Steve Jobs Theater at Apple Park, by Apple's CEO Tim Cook, with pre-orders beginning September 13, 2019 and official release on September 20, 2019.
The prominent changes from the iPhone XS are that the models feature a new triple-lens rear camera system, and the new A13 Bionic chip. The iPhone 11 Pro is Apple's first iPhone to feature a "pro" designation, which was previously reserved for larger Apple products (such as the iPad Pro). The model is the first iPhone to include an 18W fast charger in the box and a Lightning to USB-C cable allowing connection to concurrent Mac computers
Both the iPhone 11 Pro and the Pro Max are available in four colors: Gold, Space Gray, Silver, and Midnight Green. Midnight Green is a new color previously not available on iPhones. Similar to the iPhone XS, there is a notch at the front that includes the TrueDepth camera system and speaker. There is also a new rear camera design with three cameras and a flash in a larger, square-shaped bump, which is the most visible difference compared to the iPhone XS.
Both models also have a 12MP TrueDepth front camera with a f/2.0 aperture. There is a burst mode, image stabilization, HDR and a portrait mode with supporting an advanced Bokeh effect. The frontal camera also supports stabilized 4K video recording up to 60fps. Apple has added slow motion video recording to the front camera in 1080p at up to 120 fps, a feature which Apple refers to as "slofies". Similar to previous iPhone models, the TrueDepth system is also used for Face ID and Animoji.
Timeline of iPhone models
Sources: Apple Newsroom Archive